DOES HYPOTHERMIA INFLUENCE THE PREDICTIVE VALUE OF BILATERAL ABSENT N20 AFTER CARDIAC ARREST?
Citation Manager Formats
Make Comment
See Comments
This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
To the Editor:
Leithner et al.1 assessed the median somatosensory evoked potentials (SSEP) in patients treated with hypothermia after cardiac arrest. One of their 36 patients had bilateral absence of N20 potential at day 3 and eventually regained consciousness and recovered normal cognitive function. The remaining 35 patients died without awakening or entered persistent vegetative state. The authors draw the conclusion that bilateral absence of N20 as an outcome predictor needs to be reevaluated, and not used in the decision to stop therapy.
There are sparse data on the sole survivor. The patient was a 43-year-old man with alcoholism who developed pneumonia and sepsis, and had asystole for 10 minutes. SSEP testing was not repeated until 18 months later, when N20 responses were intact.
There have been 2 previous studies utilizing SSEP as a predictor in comatose patients following hypothermia. Tiainen et al.2 described 3 patients following cardiac arrest treated with hypothermia with absent N20 responses, and 8 normothermic controls with absent …
AAN Members
We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.
AAN Non-Member Subscribers
Purchase access
For assistance, please contact:
AAN Members (800) 879-1960 or (612) 928-6000 (International)
Non-AAN Member subscribers (800) 638-3030 or (301) 223-2300 option 3, select 1 (international)
Sign Up
Information on how to subscribe to Neurology and Neurology: Clinical Practice can be found here
Purchase
Individual access to articles is available through the Add to Cart option on the article page. Access for 1 day (from the computer you are currently using) is US$ 39.00. Pay-per-view content is for the use of the payee only, and content may not be further distributed by print or electronic means. The payee may view, download, and/or print the article for his/her personal, scholarly, research, and educational use. Distributing copies (electronic or otherwise) of the article is not allowed.
Letters: Rapid online correspondence
REQUIREMENTS
You must ensure that your Disclosures have been updated within the previous six months. Please go to our Submission Site to add or update your Disclosure information.
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
You May Also be Interested in
Differences in Age-related Retinal and Cortical Atrophy Rates in Multiple Sclerosis
Prof. Massimo Filippi and Dr. Paolo Preziosa
► Watch
Related Articles
- No related articles found.
Alert Me
Recommended articles
-
Articles
Somatosensory evoked potentials during mild hypothermia after cardiopulmonary resuscitationA. Bouwes, J. M. Binnekade, D. F. Zandstra et al.Neurology, November 02, 2009 -
Articles
Does hypothermia influence the predictive value of bilateral absent N20 after cardiac arrest?Christoph Leithner, Christoph J. Ploner, Dietrich Hasper et al.Neurology, March 22, 2010 -
Cases
Absence and reappearance of N20 response after thiopental withdrawal in postanoxic comaAnna Coppo, Simone Beretta, Maurizio Migliari et al.Neurology: Clinical Practice, March 19, 2015 -
Resident and Fellow Section
Clinical Reasoning: A 76-year-old man remaining comatose after cardiopulmonary resuscitationSimon C. Li, Marieke T. de Graaf, Perumpillichira J. Cherian et al.Neurology, February 03, 2014