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To the Editor:
Islam et al.1 describe an unusually high frequency of the axonal variants of Guillain-Barré syndrome (GBS) with Campylobacter jejuni infection, severe residual disability, and high mortality.
Previous reports have also shown a high proportion of axonal variants of GBS in Asia.2 However, we have several concerns about the interpretation of the outcome analysis. We are concerned about a potential selection bias in this study. Due to the relatively high mortality (14%) and severe residual disability, we suspect the results were confounded by a selection bias. The 3 hospitals involved in this study are the largest hospitals in Bangladesh, which may admit more severely ill patients than smaller facilities.
In addition, many patients …
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