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Cervical artery dissection (CAD) is now recognized as an important arterial cause of ischemic stroke in younger patients. Data concerning epidemiology, specific risk factors, and pathogenesis are accumulating but there are still no large-scale, prospective, population-based studies. Long-term follow-up and data estimating risk of recurrent CAD are needed.1–5
In this issue of Neurology, Arnold et al.6 report the results of the largest, multicenter analysis of CAD to date. Sex differences in CAD were correlated with clinical and prognostic variables. Arnold et al. found a preponderance of men; however, women were 5 years younger when CAD occurred and more often had multiple CAD. These findings are consistent with most earlier studies.1–4 In a study of 200 patients, Schievink et al.1 …
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