Efficacy of rapid IV administration of valproic acid for status epilepticus
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Abstract
Although not approved by the US Food and Drug Administration for the treatment of status epilepticus (SE), valproic acid (VPA) is an emerging option for this purpose. The authors reviewed 63 patients (30 men) with SE treated with IV VPA (average dose, 31.5 mg/kg). Analysis of demographic, clinical, and treatment information indicated an overall efficacy of 63.3% and favorable tolerance of rapid administration.
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Letters: Rapid online correspondence
- Efficacy of rapid IV administration of valproic acid for status epilepticus
- Andrea O. Rossetti, Division of Epilepsy, Department of Neurology, Brigham & Women's Hospital, 75 Francis Street, Boston, MA 02115arossetti@partners.org
- Edward B. Bromfield
Submitted March 15, 2005 - Reply to Rossetti et al
- Nita A Limdi, University of Alabama at Birmingham, 1719 6 th Avenue South, Birmingham AL 35294-0021nlimdi@uab.edu
- Faught Edward, Burneo Jorge
Submitted March 15, 2005
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