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November 12, 2002; 59 (9) Brief Communications

Aggressive behavior induced by intraoperative stimulation in the triangle of Sano

B.P. Bejjani, J.L. Houeto, M. Hariz, J. Yelnik, V. Mesnage, A.M. Bonnet, B. Pidoux, D. Dormont, P. Cornu, Y. Agid
First published November 12, 2002, DOI: https://doi.org/10.1212/01.WNL.0000031428.31861.23
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Abstract

The authors report a patient with advanced PD, successfully treated by bilateral stimulation of the subthalamic nucleus, who developed acute transient aggressive behavior during intraoperative electrical test stimulation. The electrode responsible for this abnormal behavior was located within the lateral part of the posteromedial hypothalamic region (triangle of Sano). The authors suggest that affect can be dramatically modulated by the selective manipulation of deep brain structures.

  • Received March 22, 2002.
  • Accepted July 12, 2002.
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