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Better prognostic indicators are needed for predicting the chances of survival in neurointensive care patients. Brain perfusion, usually assessed using nuclear medicine techniques, is considered a prognostic indicator. We showed that global cerebral blood flow (CBF) volume can be measured by sonography of the extracranial arteries.1 These measurements are noninvasive and can be repeatedly performed at the bedside. Reference data in children2 and in adults3,4⇓ correspond closely to those obtained with other techniques. Interobserver test-retest difference of global CBF volume measurement has been shown to be 1.7 ± 9.2%, which was comparable to a test-retest difference of 2.3 ± 8.7% found with H215O-PET measurement of CBF.5,6⇓ In this pilot observational study we determined CBF volume in neurointensive care patients in order to find out whether a critical lower threshold of cerebral perfusion can be defined above which patients eventually recovered and could be discharged and below which patients eventually died.
Subjects and methods.
In 128 patients (59 men, 69 women; mean age ± SD, 49 ± 18 years) admitted to the anesthesiologic and neurosurgical intensive care units of the University Hospital …
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