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Abstract
The authors previously reported the presence of antibody against galactocerebroside (Gal-C) in sera from patients with Guillain–Barré syndrome subsequent to Mycoplasma pneumoniae infection. Anti-Gal-C antibody activities in these sera were inhibited specifically by the M. pneumoniae reagent. A rabbit anti-Gal-C antibody recognized several glycolipids in M. pneumoniae. These data show that a Gal-C-like structure is present in M. pneumoniae, indicative of molecular mimicry between a major myelin glycolipid, Gal-C, and M. pneumoniae.
- Received February 19, 2001.
- Accepted April 4, 2001.
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