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There are many ways to apply a pain stimulus to a comatose patient to elicit a motor response. [1-4] Physicians have different preferences with regard to noxious pain stimuli. An ideal pain stimulus in coma must respect the patient, result in a motor response if elicitable, and not be associated with a significant sympathetic or vagal response or cause bruising.
Many noxious stimuli have been suggested, including twisting of the forearm, pinprick on several body locations, rubbing the knuckles …
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