Reversible Dysexecutive Syndrome From CSF Overshunting in a Patient With Normal Pressure Hydrocephalus
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A 72-year-old male science teacher with normal pressure hydrocephalus presented 1 year after ventriculoperitoneal (VP) shunt placement with neck pain, behavioral changes, and nonamnestic cognitive decline. Six months prior, his shunt was adjusted from 4 to 3. Montreal Cognitive Assessment was 21/30 with dysexecutive predominance. EEG was unremarkable. CSF Alzheimer disease biomarkers were borderline. MRI (Figure 1) found overshunting. After shunt adjustments (3–4), his cognitive and behavioral symptoms resolved. Repeat Montreal Cognitive Assessment after 4 months was 29/30 with sustained remission after 1 year. Intracranial hypotension, whether from VP shunting or spontaneous CSF leak,1,2 may cause reversible dysexecutive cognitive impairment.
Footnotes
Go to Neurology.org/N for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the article.
↵* These authors contributed equally to this work.
Submitted and editor reviewed. The handling editor was Editor-in-Chief José G. Merino, MD, MPhil, FAHA, FAAN.
- Received March 10, 2022.
- Accepted in final form May 19, 2022.
- © 2022 American Academy of Neurology
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