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Dementia affects approximately 50 million people around the world.1 There are almost 10 million new cases diagnosed every year, and due to demographic shifts towards aging, this figure is predicted to triple by 2050, along with increasing disability and reduced quality of life for those with cognitive impairment and caregivers. Alzheimer disease (AD), the most common cause of dementia, is characterized by an initial deterioration of episodic memory followed by impairment in naming and executive function, among other cognitive domains. β-Amyloid and neurofibrillary tangles brain deposition are its hallmarks. Vascular dementia (VaD), the second most common cause, is characterized by evidence of cerebrovascular disease.
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