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Asken et al.1 assessed a probable serum marker of concussion. Previously, I noted that the ideal serum biomarker can be clinically used to stratify traumatic concussion injury according to graded severity level, aid in confirmation of diagnosis, predict adverse secondary injury events including clinical worsening, predict the need of continuity of medical or neurosurgical intervention, guide appropriate application and modification of various treatment modalities, predict effectiveness of management methods, and predict prognostic outcome. Furthermore, its trend of serum level course over days, factors affecting serum level and relation over course of concussion management, should be well known.2
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- © 2019 American Academy of Neurology
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