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We thank Dr. Marinelli for the comment on our article,1 and agree that further research into the relationship between protein misfolding and weight loss in Parkinson disease (PD) is needed. Furthermore, several other potential mechanisms for weight loss deserve further study, including other aspects of brain metabolism, whole-body metabolic rate, appetite regulation, and food-related reward mechanisms.
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Author disclosures are available upon request (journal{at}neurology.org).
- © 2018 American Academy of Neurology
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