This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
Multiple system atrophy (MSA) is a rare adult-onset rapidly progressive fatal neurodegenerative disorder characterized by the abnormal aggregation of misfolded α-synuclein primarily in oligodendrocytes.1
Acknowledgments
Acknowledgment: The authors thank the patients with MSA who donated their organs and Dr. Tatiana Bakaeva for her help with the autopsies.
Footnotes
↵* These authors contributed equally to this work.
Supplemental data at Neurology.org
Author contributions: Dr. Mendoza-Santiesteban: study concept and design, acquisition of data, analysis and interpretation, critical revision of the manuscript for important intellectual content, study supervision. Dr. Palma: study concept and design, acquisition of data, analysis and interpretation, critical revision of the manuscript for important intellectual content, study supervision. I. Ortuño-Lizaran: acquisition of data, analysis and interpretation, critical revision of the manuscript for important intellectual content. Dr. Cuenca: acquisition of data, analysis and interpretation, critical revision of the manuscript for important intellectual content. Dr. Kaufmann: study concept and design, critical revision of the manuscript for important intellectual content, study supervision.
Study funding: NIH (U54-NS065736-01), Multiple System Atrophy Coalition, Michael J. Fox Foundation, Dysautonomia Foundation, Regional Government of Valencia (Prometeo 2016/158), Spanish Health Research Institute Carlos III (ISCIII RETICS-FEDER RD12/0034/0010), Ministry of Economy of Spain (MINECO-FEDER-BFU2015-67139-R), and Ministry of Education of Spain (FPU14/03166).
Disclosure: C. Mendoza-Santiesteban receives research support from The Dysautonomia Foundation and the Michael J. Fox Foundation. J. Palma receives research support from the NIH (U54NS065736), the Food and Drug Administration, the Dysautonomia Foundation, the MSA Coalition, and the Michael J. Fox Foundation. I. Ortuño-Lizaran receives financial support from the Ministry of Education of Spain. N. Cuenca receives research support from the Regional Government of Valencia, Spanish Health Research Institute Carlos III, and the Ministry of Economy of Spain. H. Kaufmann serves as Editor-in-Chief of Clinical Autonomic Research and receives research support from the NIH, the Food and Drug Administration, the Dysautonomia Foundation, and the Michael J. Fox Foundation. Go to Neurology.org for full disclosures.
- Received December 29, 2016.
- Accepted in final form March 15, 2017.
- © 2017 American Academy of Neurology
AAN Members
We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.
AAN Non-Member Subscribers
Purchase access
Letters: Rapid online correspondence
REQUIREMENTS
You must ensure that your Disclosures have been updated within the previous six months. Please go to our Submission Site to add or update your Disclosure information.
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
