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Primary CNS (PCNS) lymphoma accounts for less than 3% of all primary brain tumors1; primary extranodal marginal zone B cell lymphoma of the CNS, which includes the mucosa-associated lymphoid tissue (MALT) lymphoma subtype, is extremely rare, comprising up to 5.4% of PCNS lymphomas.2 PCNS MALT lymphomas are localized, low-grade lesions that occur more frequently in women, often present with indolent neurologic symptoms and focal seizures, and manifest as meningioma-like dural-based discrete masses on neuroimaging.3,4 This case illustrates a novel presentation of a rare CNS malignancy.
Footnotes
Author contributions: Deana M. Gazzola: manuscript content, writing/editing for intellectual content. Arnaldo A. Arbini: figure content, writing/editing for intellectual content. Karen Haglof: contribution of clinical information, editing of manuscript for intellectual content. Steven Pacia: contribution of clinical information, writing/editing for intellectual content.
Study funding: No targeted funding reported.
Disclosure: The authors report no disclosures relevant to the manuscript. Go to Neurology.org for full disclosures.
- Received February 10, 2016.
- Accepted in final form June 1, 2016.
- © 2016 American Academy of Neurology
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- Author response to Kunchok et al.
- Low-grade, localized, primary extra-nodal marginal zone B-cell leptomeningeal lymphoma
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