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Abnormalities of eating behavior, of which there are a variety, are signal features of frontotemporal dementia (FTD), as exemplified by their stipulation in contemporary diagnostic criteria. The study by Ahmed et al.1 examines physiologic correlates of eating disorder in behavior-variant FTD (bvFTD) and semantic-variant primary progressive aphasia (svPPA) by analyzing linkages among body mass index (BMI), peptide hormones, and hypothalamic volumes.1 The contrasts with Alzheimer disease (AD) are informative, but more might have been learned from comparisons with counterparts who did not have an eating disorder.
Footnotes
Study funding: No targeted funding reported.
Disclosure: C.U. Onyike serves/has served a consultant to Eli Lilly, Pfizer, and clinical investigator in trials sponsored by Forest Pharmaceuticals, GE Health care. and TauRX. Go to Neurology.org for full disclosures.
- © 2015 American Academy of Neurology
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