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Abstract
Objective: The purpose of this study was to determine the prevalence of bicuspid aortic valves (BAVs) and thoracic ascending aortic aneurysms (TAAs) in a retrospective cohort of patients treated for intracranial aneurysms (IAs).
Methods: Patients treated for IA at our institution between 2002 and 2011 were identified and their clinical records reviewed. Those without an echocardiogram of sufficient quality to assess the aortic valve were excluded. The prevalence of BAVs and TAAs in this remaining cohort was determined based on echocardiography reports, medical records, and cross-sectional chest imaging.
Results: Of 1,047 patients, 317 had adequate echocardiography for assessment of BAV. Of these, 82 also had cross-sectional chest imaging. Of the 317 patients, 2 had BAV and 15 had TAA. The prevalence of BAVs (0.6%, 95% confidence interval 0.2%–2.2%) was similar to population prevalence estimates for this condition; however, the prevalence of TAAs (4.7%, 95% confidence interval 2.9%–7.6%) was larger than expected in a normal age- and sex-matched population.
Conclusions: Our data demonstrate an association between IA and TAA, but not independently for BAV.
GLOSSARY
- BAV=
- bicuspid aortic valve;
- CI=
- confidence interval;
- IA=
- intracranial aneurysm;
- TAA=
- thoracic aortic aneurysm;
- TEE=
- transesophageal echocardiogram;
- TTE=
- transthoracic echocardiogram
Footnotes
Go to Neurology.org for full disclosures. Funding information and disclosures deemed relevant by the authors, if any, are provided at the end of the article.
- Received March 15, 2014.
- Accepted in final form September 18, 2014.
- © 2014 American Academy of Neurology
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