B-cell depletion in children with neuroimmunologic conditions
The learning curve
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The study by Dale et al.,1 “Utility and safety of rituximab in pediatric autoimmune and inflammatory CNS disease,” is an important contribution to the limited available information about tolerability of disease-modifying treatments for neuroimmunologic conditions in children. In this work, 15 pediatric centers worldwide used a standardized questionnaire to survey retrospectively rituximab use, dosage, safety, and disease outcomes evaluated by modified Rankin Scale.
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- © 2014 American Academy of Neurology
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