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Chronic and acute (minor) infections or inflammatory conditions are associated with an increased risk for cerebral ischemic stroke in adults.1–3 Stroke etiology is different in children, is probably multifactorial, and may be elusive. Minor infections are common in children and lead to similar systemic and especially prothrombotic changes as in adults. Because conventional vascular risk factors are less prevalent in children, inflammatory conditions may be more relevant contributors to stroke risk in children. However, data on the association of inflammation and pediatric stroke are scarce. In this issue of Neurology®, Hills et al.4 present their work on the association of minor infections with the risk of stroke in children.
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Go to Neurology.org for full disclosures. Funding information and disclosures deemed relevant by the author, if any, are provided at the end of the editorial.
See page 890
- © 2014 American Academy of Neurology
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