Rapid development of 9 cerebral aneurysms in varicella-zoster virus vasculopathy
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A patient with zoster in multiple dermatomes, severe headache, and normal magnetic resonance angiography (MRA) and 4-vessel digital subtraction angiogram (DSA) developed 9 anterior circulation aneurysms 2 months later. Antiviral treatment resulted in clinical improvement, size reduction of most aneurysms, and complete resolution of the 2 largest aneurysms.
Acknowledgments
Acknowledgment: The authors thank Marina Hoffman for reviewing the manuscript for errors in grammar, punctuation, spelling, readability, clarity, and accuracy.
Footnotes
Author contributions: Drs. Liberman, Hurley, Caprio, Bernstein, Nagel, and Gilden all contributed to drafting/revising the manuscript for content, study concept/design, analysis or interpretation of data, vital reagents/tools/patents, and acquisition of data.
Study funding: Supported in part by NIH grants AG006127 and AG032958 to D.G. and NS067070 to M.A.N.
Disclosure: The authors report no disclosures relevant to the manuscript. Go to Neurology.org for full disclosures.
- Received November 20, 2013.
- Accepted in final form March 3, 2014.
- © 2014 American Academy of Neurology
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