This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
To the Editor:
I read with interest the article by Scheid et al.,1 who describe 3 patients with chorea-acanthocytosis (ChAc) whose initial symptomatology included partial complex seizures (PCS). The brain MRI, in addition to caudate atrophy, showed mesial temporal sclerosis (MTS) in all 3 cases.
As the authors suggest, it is intriguing that a pathologic process with a predilection for the basal ganglia should cause focal abnormalities in the hippocampal region. The authors posit several theories but do not mention genetic abnormalities, which have been theorized as a contributing factor in MTS.
In addition, since MTS is the most common pathology in temporal lobe seizures, its occurrence in ChAc may be coincidental. The authors doubt the significance of the seizures themselves as a culprit behind MTS in their patients. However, seizures—particularly …
AAN Members
We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.
AAN Non-Member Subscribers
Purchase access
Letters: Rapid online correspondence
REQUIREMENTS
You must ensure that your Disclosures have been updated within the previous six months. Please go to our Submission Site to add or update your Disclosure information.
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
You May Also be Interested in
Long-term Safety and Efficacy of Avalglucosidase Alfa in Patients With Late-Onset Pompe Disease
Dr. Marianne de Visser and Dr. Maudy Theunissen
► Watch
Alert Me
Recommended articles
MRI and EEG as long-term seizure outcome predictors in familial mesial temporal lobe epilepsy
Temporal lobe epilepsy in childhood: Clinical, EEG, and neuroimaging findings and syndrome classification in a cohort with new-onset seizures
Entorhinal cortex in temporal lobe epilepsy
11C-flumazenil PET, volumetric MRI, and quantitative pathology in mesial temporal lobe epilepsy