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To the Editor:
I read with interest the article by Mehta et al.1 on race/ethnic differences in Alzheimer disease (AD). Race/ethnicity was classified as Latino/non-Latino white, African American, Asian/Pacific Islander (Asian), American Indian, and of other or unknown race.
This classification stems from a governmental designation of race and ethnicity.2 Within each of these racial/ethnic groups there is tremendous genetic and cultural heterogeneity due to the heterogeneous extraction of racial/ethnic groups in the United States. These differences may obscure possible conclusions regarding the finding that African American and Latino populations have longer survival compared to white populations with AD.
Further details regarding the Latino/Hispanic subjects are not included in the text. The racial makeup of this group is unclear (i.e., African American, mulatto, Mestizo, Native American, Caucasian).
Given our multicultural society, we should strive to use more precise markers of genotypic, cultural, and …
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