THALAMIC VO-COMPLEX VS PALLIDAL DEEP BRAIN STIMULATION FOR FOCAL HAND DYSTONIA
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Focal hand dystonia (FHD) is a primary dystonia produced by the excessive co-contraction of antagonistic muscles of the hand and forearm.1,2 Although deep brain stimulation (DBS) is now recognized as a beneficial option to treat a wide spectrum of dystonias,3 little is known regarding its effects on FHD. This is a report of DBS of the thalamic Vo-complex nucleus or the globus pallidus internus (GPi) effecting the complete, sustained relief of medically intractable FHD. The term Vo-complex refers to the combination of the ventralis oralis anterior nucleus (Voa) and ventralis oralis posterior nucleus (Vop) of the thalamus.
Case report.
A 34-year-old right-handed man without a notable medical history experienced gradual onset of writer's cramp of the right hand beginning at age 31. At age 32 he also noted progressively worsening stiffness of the fingers and wrist of his left hand. As the focal injection of botulinum toxin and sequential pharmacologic trials that included clonazepam, baclofen, and etizolam produced unsatisfactory results, they were discontinued.
On admission, his physical and mental condition was normal. Brain MRI and laboratory studies revealed no abnormal findings. The causes of secondary dystonia were excluded as far as possible. There were no neurologic abnormalities except for …
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