IMPACT OF COGNITIVE RESERVE ON THE RELATIONSHIP OF LEAD EXPOSURE AND NEUROBEHAVIORAL PERFORMANCE
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To the Editor:
Bleecker et al. conclude that lead smelter workers with lower cognitive reserves (CR) were more susceptible to the effects of lead on cognitive performance tests than workers with higher CR.1 The authors do not mention why some workers had a lower CR.
One hypothesis is that some workers—as children—may have been exposed disproportionately to high levels of lead. Antenatal and postnatal exposure to environmental lead has been shown to result in cognitive deficits that persist into later childhood and adulthood.2,3
The smelter’s work force was drawn from the community (Belledune, New Brunswick) where the smelter was located and from surrounding communities (personal communications with retired smelter workers). Many smelter workers were children or not yet born when the smelter began operating (1966). The smelter was built less than 1 kilometer from the school and church. Dust testing in 1968 by investigators with the Department …
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