This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
To the Editor:
Rudnicki described a patient with Lambert-Eaton myasthenic syndrome (LEMS) and small cell lung carcinoma (SCLC) who presented with isolated ocular weakness.1
We agree with the author that this rare presentation of LEMS might be confused with purely ocular seronegative myasthenia. However, we want to stress that the absence of ocular weakness is a more frequent cause of failure to diagnose LEMS. Proximal leg weakness without ptosis or diplopia is frequently not recognized as a neuromuscular transmission disorder.
Rudnicki states that the prevalence of ocular symptoms in LEMS shows a wide range (0 to 65%).2,3 However, this is probably due to observer bias. Wirtz et al.2 studied the initial symptoms at disease onset, whereas Burns et al.3 described the symptoms present at diagnosis (median 8 months). …
AAN Members
We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.
AAN Non-Member Subscribers
Purchase access
Letters: Rapid online correspondence
REQUIREMENTS
You must ensure that your Disclosures have been updated within the previous six months. Please go to our Submission Site to add or update your Disclosure information.
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
