Speech and language delay are early manifestations of juvenile-onset Huntington disease
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Abstract
The neurocognitive features of juvenile-onset Huntington disease (HD) are not well understood. We present three patients with onset of HD symptoms before age 10 years in whom speech delay was the first symptom. Speech delay predated motor symptoms by at least 2 years, and language function was consistently impaired on formal testing. Screening for speech delay is particularly important in children with a family history of HD.
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Letters: Rapid online correspondence
- Speech and language delay are early manifestations of juvenile-onset Huntington disease
- Peter B. Rosenberger, MD, 5 Whittier Place, #102A, Boston, MA 02114prosenberger@massmed.org
Submitted December 12, 2006 - Reply from the Authors
- Adam L. Boxer, UCSF, 350 Parnassus Avenue, Suite 706, Box 1207, San Francisco, CA, 94143-1207aboxer@memory.ucsf.edu
- Grace Yoon
Submitted December 12, 2006
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