Significance of phrenic nerve electrophysiological abnormalities in Guillain–Barré syndrome
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Abstract
The authors investigated whether the amplitude and latency of diaphragm compound muscle action potential helped predict respiratory failure in Guillain–Barré syndrome. Both variables were significantly but weakly correlated with vital capacity (VC) and were similar in unventilated (n = 60) and ventilated (n = 10) patients. In ventilated patients, motor loss severity, progression, and VC reduction were significantly greater, and bulbar dysfunction was more common. Predicting respiratory failure must rely on clinical features and VC.
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Letters: Rapid online correspondence
- Significance of phrenic nerve electrophysiological abnormalities in Guillain–Barré syndrome
- Charles F. Bolton, Queen's University, Etherington Hall, Room 3008, Queen's University, Kingston, Ontario, K7L 3N6, Canadacb41@post.queensu.ca
Submitted March 29, 2006 - Reply from the authors
- Tarek Sharshar, Hôpital Raymond Poincaré, Service de Réanimation,104 Boulevard Raymond Poincaré 92380 Garches Francetarek.sharshar@rpc.ap-hop-paris.fr
- Frédéric Lofaso, MD, PhD, Garches, France
Submitted March 29, 2006
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