This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
The Late Breaking Science Abstracts were originally presented at the 57th American Academy of Neurology Annual Meeting in Miami Beach, FL. These abstracts highlight the most current research by neurologists, neuroscientists, and other applicable researchers whose work is of major scientific importance or interest, warranting expedited presentation and publication. Key aspects of the research must have been conducted after the November 3 abstract deadline. Because of the late deadline for these abstracts, they were not included in the Program Issue.
OBJECTIVE:
To evaluate the efficacy and safety of rufinamide adjunctive therapy in patients with Lennox-Gastaut (LGS) syndrome.
BACKGROUND:
Lennox-Gastaut syndrome is a catastrophic childhood epileptic encephalopathy characterized by multiple types of treatment resistant seizures. Despite the demonstrated efficacy of a few newer antiepileptic medications (AEDs) for patients with LGS, significant numbers of LGS patients continue to experience seizures. Due to its potential broad spectrum of activity against seizures and the …
AAN Members
We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.
AAN Non-Member Subscribers
Purchase access
Letters: Rapid online correspondence
REQUIREMENTS
You must ensure that your Disclosures have been updated within the previous six months. Please go to our Submission Site to add or update your Disclosure information.
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
You May Also be Interested in
Alert Me
Recommended articles
Rufinamide for generalized seizures associated with Lennox–Gastaut syndrome
Lamotrigine extended-release as adjunctive therapy for partial seizures
A double-blind, randomized trial of topiramate in Lennox–Gastaut syndrome
Double-blind, placebo-controlled study of lamotrigine in primary generalized tonic-clonic seizures