APOE ε4 is not a susceptibility gene in idiopathic or diabetic sensory neuropathy
Citation Manager Formats
Make Comment
See Comments
![Loading Loading](https://n.neurology.org/sites/all/modules/contrib/panels_ajax_tab/images/loading.gif)
This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
Abstract
The presence of an APOE ε4 allele may be a risk factor for neuropathy severity in diabetes. The authors assessed the frequency of APOE ε4 in patients presenting with sensory predominant neuropathy. APOE ε4 frequency among patients with early diabetic neuropathy and impaired glucose tolerance–associated neuropathy was 16 to 17%, and not different from patients with idiopathic neuropathy (17%) or published normative values (16%). APOE ε4 may not function as a susceptibility gene in sensory predominant neuropathy.
- Received April 14, 2004.
- Accepted August 18, 2004.
AAN Members
We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.
AAN Non-Member Subscribers
Purchase access
For assistance, please contact:
AAN Members (800) 879-1960 or (612) 928-6000 (International)
Non-AAN Member subscribers (800) 638-3030 or (301) 223-2300 option 3, select 1 (international)
Sign Up
Information on how to subscribe to Neurology and Neurology: Clinical Practice can be found here
Purchase
Individual access to articles is available through the Add to Cart option on the article page. Access for 1 day (from the computer you are currently using) is US$ 39.00. Pay-per-view content is for the use of the payee only, and content may not be further distributed by print or electronic means. The payee may view, download, and/or print the article for his/her personal, scholarly, research, and educational use. Distributing copies (electronic or otherwise) of the article is not allowed.
Letters: Rapid online correspondence
REQUIREMENTS
You must ensure that your Disclosures have been updated within the previous six months. Please go to our Submission Site to add or update your Disclosure information.
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
You May Also be Interested in
Dr. Deborah Friedman and Dr. Stacy Smith
► Watch
Related Articles
- No related articles found.
Topics Discussed
Alert Me
Recommended articles
-
Articles
Epidermal nerve fiber density and sural nerve morphometry in peripheral neuropathiesD.N. Herrmann, J.W. Griffin, P. Hauer et al.Neurology, November 01, 1999 -
Articles
Impaired reinnervation in HIV infection following experimental denervationK. Hahn, A. Triolo, P. Hauer et al.Neurology, April 16, 2007 -
Articles
Small-fiber neuropathy in patients with ALSJ. Weis, I. Katona, G. Müller-Newen et al.Neurology, June 06, 2011 -
Brief Communications
Painful small-fiber neuropathy in Sjögren syndromeJ. Chai, D. N. Herrmann, M. Stanton et al.Neurology, September 26, 2005