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There are numerous case reports in which a spinal cord inflammatory demyelinating plaque subsequently develops into a syrinx, probably by cavitation.1-3⇓⇓ Despite this, current neurologic teaching does not generally consider multiple sclerosis (MS) in the differential diagnosis of syringomyelia. We present the case of a woman aged 48 years who sought treatment for a progressive myelopathy secondary to syringomyelia and who, although not meeting McDonald criteria, most likely had MS.4
Case report.
A woman aged 48 years sought treatment for a 5-year history of progressive spastic paraparesis, urinary frequency and incontinence, and tingling of her toes. She denied other neurologic symptomatology. She was myopic and presbyopic and wore glasses for distance vision and reading. Her overall health was normal with no acknowledged medical problems. There was no family history of neuromuscular disease. Six years before the onset of the weakness of her legs she had pain in her left upper limb for ∼2 months. Numerous investigations, which included formal neurologic evaluation, MRI of the brain, EMG of the left …
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