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Abstract
A 74-year-old patient with idiopathic Parkinson’s disease was evaluated for unintended sleep episodes that occurred after long-term treatment with 400 mg/day of l-dopa. Overnight sleep studies and multiple sleep latency testing were carried out under double-blind administration of either l-dopa or placebo. Mean sleep latency with l-dopa was 7 minutes, in contrast to a normal value of 19 minutes, 25 seconds with placebo. The authors’ results suggest that l-dopa may cause daytime somnolence in some patients with Parkinson’s disease.
- Received October 28, 2002.
- Accepted June 14, 2003.
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