Assessment of a DJ-1 (PARK7) polymorphism in Finnish PD
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Abstract
Mutations in DJ-1 are a cause of autosomal recessive parkinsonism. Polymorphism of genes implicated in hereditary forms of parkinsonism may be a predisposing factor in sporadic Parkinson’s disease (PD). The authors analyzed whether a polymorphism (g.168_185del) within exon 1 of DJ-1 contributes to the risk of sporadic PD in a Finnish case-control series. This gene does not play a major role in the genetic predisposition to PD in this population.
- Received January 29, 2003.
- Accepted June 10, 2003.
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Letters: Rapid online correspondence
- Assessment of a DJ-1 (PARK7) polymorphism in Finnish PD.
- Daniel G Healy, Department of Molecular Neuroscience, Institute of Neurology, Queen Square, London WC1N3BG., Department of Molecular Neuroscience, Institute of Neurology, Queen Square, London WC1N3BG.d.healy@ion.ucl.ac.uk
- Patrick Abou-Sleiman, Shushant Jain, Kourosh R . Ahmadi and Nicholas W. Wood
Submitted December 17, 2003
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