This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
Highly active antiretroviral therapy (HAART) has decreased opportunistic infections (OI) and AIDS deaths. Institution of HAART in advanced AIDS, however, may be complicated by the immune reconstitution syndrome (IRS)—inflammatory reactions leading to autoimmune diseases or atypical manifestations of OI.1
Case report.
A 31-year-old man had progressive gait difficulty over 4 weeks. Examination revealed left leg weakness with impaired vibratory and position sense and pin and temperature loss to T5 on the right. HIV serology was positive with CD4 count 35/mm3 and viral load 26,000 copies/mL. Spine MRI showed a 1-cm enhancing, intradural, extramedullary mass at left T4 (figure, A). Results of cranial MRI were normal. Lumbar puncture revealed protein 153 mg/dL, glucose 37 mg/dL, and 73 white blood cells/mm3 (81% lymphocytes). Chest film was normal; purified protein derivative and controls were unreactive. The mass was resected. Pathology revealed abundant acid-fast organisms. Specific mycobacterial organism was not identified. Four agents against Mycobacterium tuberculosis (MTB) were begun; clarithromycin was added to cover Mycobacterium avium complex (MAC). Postoperatively, motor examination normalized. Mild sensory deficits …
AAN Members
We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.
AAN Non-Member Subscribers
Purchase access
Letters: Rapid online correspondence
REQUIREMENTS
You must ensure that your Disclosures have been updated within the previous six months. Please go to our Submission Site to add or update your Disclosure information.
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
