This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
To the Editor:
Charles et al. make an important contribution with their article describing possible predictors of deep brain stimulation (DBS) of the subthalamic nucleus efficacy for PD.1 While DBS is highly effective and FDA approved, the procedure has considerable risks. Effective predictors could favorably shift the risk-to-benefit ratio. Unfortunately, the analysis performed is of limited value and potentially misleading.
A more appropriate analysis would be to report the area under the receiver–operator characteristic curve, which relates the specificity and sensitivity of the tests to age and levodopa responsiveness. The goal of any predictive task not only is to avoid surgery for those patients not likely to benefit but also to avoid withholding surgery from those that would. Visual inspection of the data …
AAN Members
We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.
AAN Non-Member Subscribers
Purchase access
Letters: Rapid online correspondence
REQUIREMENTS
You must ensure that your Disclosures have been updated within the previous six months. Please go to our Submission Site to add or update your Disclosure information.
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
You May Also be Interested in
Hastening the Diagnosis of Amyotrophic Lateral Sclerosis
Dr. Brian Callaghan and Dr. Kellen Quigg
► Watch
Alert Me
Recommended articles
Comparative effects of unilateral and bilateral subthalamic nucleus deep brain stimulation
A meta-regression of the long-term effects of deep brain stimulation on balance and gait in PD
Deep brain stimulation in early-stage Parkinson disease
Subthalamic nucleus stimulation modulates afferent inhibition in Parkinson disease