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To the Editor:
Noonan et al.1 estimated the prevalence of MS in the United States to be 211,000 (±20,000) based on the National Health Interview Survey (NHIS). The authors are correct to point out significant sampling and other limitations of the NHIS. Once the questionable case ascertainment, reliance on patient recall, use of proxy information, and noninclusion of institutionalized patients are taken into account, an adjusted prevalence estimate is more in line with previous estimates.2
The National MS Society counts some 280,000 individuals with MS on its membership rolls. A recent survey undertaken by Roper–Starch Worldwide to learn more about individuals with MS who are not members of the Society suggested that its MS membership may represent about two-thirds of the population of MS in the United States. Anderson et al.2 indicated a prevalence range of 250,000 to 350,000 in the United States in the early 1990s. Both studies suggest a higher prevalence …
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