Cycad neurotoxins, consumption of flying foxes, and ALS-PDC disease in Guam
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Abstract
The Chamorro people of Guam have been afflicted with a complex of neurodegenerative diseases (now known as ALS-PDC) with similarities to ALS, AD, and PD at a far higher rate than other populations throughout the world. Chamorro consumption of flying foxes may have generated sufficiently high cumulative doses of plant neurotoxins to result in ALS-PDC neuropathologies, since the flying foxes forage on neurotoxic cycad seeds.
- Received October 10, 2001.
- Accepted December 18, 2001.
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Letters: Rapid online correspondence
- Reply to Letter to the Editor
- Paul Alan Cox, National Tropical Botanical Garden Kalaheo Kauaimkasay@ntbg.org
- Oliver W Sacks
Submitted June 27, 2002 - Cycad neurotoxins, consumption of flying foxes, and ALS-PDC disease in Guam
- Kwang-Ming Chen, Lytico and Bodig Research Project Magilao Guamsandi_moriarity@urmc.rochester.edu
- Ulla K Craig, Chin-Tian Lee, and Robert Haddock
Submitted June 27, 2002
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