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A view of status epilepticus as a monolithic disorder requiring a standardized, cookbook type of approach to management is often promoted. This popular “one size fits all” philosophy has its advantages. It emphasizes the importance of early diagnosis and prompt therapy, and offers simple, easy-to-follow protocols for acute diagnosis and treatment. However, in this issue of Neurology, Logroscino et al.1 demonstrate that one size does not fit all patients when it comes to long-term mortality, defined as cumulative mortality at 10 years following a first episode of status in patients who survived for 30 days. Their findings confirm and extend similar previous observations on differences among patients in short-term studies of mortality, prognosis, and outcome of status epilepticus,2-5⇓⇓⇓ and have implications for the care of patients with status.
Indeed, there appear to be important pre-existing clinical factors that significantly influence the short and long-term mortality for patients with status epilepticus, the major …
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