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Attention-deficit hyperactivity disorder (ADHD) and tics/Tourette syndrome (TS) are common developmental disorders. Stimulants are the mainstay of treatment for ADHD with approximately 85% of children improving appreciably. However, questions have been raised about their use because of reports describing the appearance or exacerbation of tics/TS in children treated with stimulants for ADHD.1,2⇓ Persisting caveats (even in the current Physician’s Desk Reference) against the use of stimulants in children with tics/ TS, a family history of tics/TS, or those developing tics while on stimulants have proved extremely problematic in treatment planning. Tics/TS are common in children with ADHD (occurring in as many as 50%),1,3⇓ and ADHD is even more common in children with tics/TS (occurring in up to 90%).4 Several recent stimulant vs placebo-controlled crossover studies in children with ADHD and tics/TS and a few prospective natural history studies of children with tics/TS and children who developed tics during stimulant treatment have not shown a significant or unacceptable increase in tics on stimulant treatment.1-3,5,6⇓⇓⇓⇓ Increases in tics …
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