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We report two patients who had hemorrhagic strokes (one parenchymal hemorrhage secondary to an arteriovenous malformation and one subarachnoid hemorrhage) associated with the use of sumatriptan.
Cerebrovascular disorders due to a complication of triptan use are rare, although cases suggesting such a relationship have been reported.1
Patient 1.
A 44-year-old normotensive woman in good health had been having migraine for 15 years, fulfilling the International Headache Society criteria for migraine with aura. The auras were left visual field disturbances typically preceding the headaches. She had no other medical or surgical history. She had utilized sumatriptan without complication. On the day she was admitted to the hospital, she had a migraine without aura. She took a first subcutaneous injection of sumatriptan (6 mg) without relief. Two hours later, she took a second dose, which was followed 30 minutes later by an increase in the intensity of her headaches, nausea, and vomiting. She then developed a left hemiplegia and finally lost consciousness. In …
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Letters: Rapid online correspondence
- Intracranial hemorrhages associated with sumatriptan
- Reply to Letters from Spierlings and Mulder
- Intracranial hemorrhages associated with sumatriptan
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