Encephalitis associated with Chlamydia pneumoniae
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Chlamydia pneumoniae is known to cause acute respiratory infections. However, in recent years it has also been associated with several chronic diseases including reactive arthritis and coronary artery disease.1 Neurologic complications associated with C pneumoniae infection are rare,2-7⇓⇓⇓⇓⇓ with specific antibody production to C pneumoniae in the CSF demonstrated in only two cases.2,6⇓ We describe a patient who had fever, pharyngitis, and lymphadenopathy followed by encephalitis and serologic evidence for C pneumoniae.
Case report.
A 33-year-old woman was admitted to the hospital on 20 August 1999 with fever (38.5 °C), enlarged lymph nodes, and sore throat. Initial laboratory investigation revealed a mild leukopenia (2.7 × 109/L, 83% neutrophils), mild thrombocytopenia (75 × 109/L), and an elevated serum C-reactive protein concentration (47 mg/L; normal value <10 mg/L). A few days later, the patient became drowsy and confused, and an EEG displayed slow wave activity with frontotemporal bilateral …
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