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A 27-year-old man presented with headache, bitemporal hemianopia, memory deficit, gait disturbance, and impotence. MRI revealed a giant pituitary tumor (figure). Serum prolactin level was initially reported as 78 ng/mL. The slightly elevated prolactin was falsely attributed to stalk effect. The patient was scheduled for surgery. When the prolactin assay was repeated on a 1:100 times diluted serum specimen, the result was greater than 2000 ng/mL (estimated 280,000 ng/mL). Surgery was cancelled. The patient was treated with …
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