Remission of HIV myelopathy after highly active antiretroviral therapy
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Human immunodeficiency virus–associated myelopathy (HM) is a common neurologic complication of AIDS. It usually presents late in HIV infection and is rarely the first sign of AIDS.1,2 The course is invariably progressive and leads to severe, spastic paralysis of the lower limbs and autonomic dysfunction. With the initiation of protease inhibitors in the treatment of HIV, patients have greater life expectancy.3,4 Highly active antiretroviral therapy (HAART) uses various combinations of reverse transcriptase and protease inhibitors and has not yet been reported to prevent the progression of HM. It has been suggested that HAART may not be so active against HIV in the CNS.4,5 We report a patient with HM who dramatically improved after the initiation of HAART.
Case report.
A 35-year-old man had a 4-month history of progressive weakness in the lower limbs, impotence, …
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