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There currently is great interest in the potential therapeutic uses of cannabis in MS.1 We report the dramatic suppression of acquired pendular nystagmus in a patient with MS after smoking cannabis resin but not after taking nabilone tablets or orally administered capsules containing cannabis oil.
Methods.
A home office license was obtained to study this single patient for a 3-month period, and the study was approved by the Riverside Health Authority Ethics Committee. Cannabis oil-containing capsules were prepared as described previously.2,3 Each capsule contained approximately 5 mg of tetrahydrocannabinol (THC). The patient’s eye movements were recorded using an infrared limbus tracker (Skalar IRIS) in vertical recording mode. The system has a resolution of 2 minutes of arc, and the vertical recording range is between ±20°. The system was calibrated by asking the subject to follow a sequence of nine light-emitting diodes located at different vertical positions on the screen. Serial blood samples were taken …
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