Cytomegalovirus infection and Guillain-Barré syndrome
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To the Editor: We read with interest the article by Visser et al.1 They reported that cytomegalovirus (CMV)-related Guillain-Barré syndrome (GBS) patients may have a different clinical pattern in comparison with other GBS groups. Also reported was that CMV-related GBS patients were significantly younger, initially had a severe course indicated by a high frequency of respiratory insufficiency, and often developed cranial nerve involvement and severe sensory loss. The findings, however, did not prove an etiologic relationship between CMV infection and different clinical pattern of GBS.
Guillain-Barré syndrome is a postinfectious polyneuropathy that causes demyelination in mainly motor but sometimes sensory nerves. The paralysis usually follows a nonspecific viral infection by about 10 days. The original …
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