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Chronic exposure to the solvent methyl ethyl ketone and other related compounds may cause peripheral neuropathy, [1] and acute exposure may cause ataxia and tremor. [2] We describe a patient, exposed occupationally to methyl ethyl ketone, who developed multifocal myoclonus, ataxia, and postural tremor. These signs disappeared after cessation of the exposure.
Case report.
A 27-year-old man without a family history of movement disorders was admitted to the hospital in January 1994 because of involuntary movements and gait difficulty. He denied taking any drugs or alcohol. During the last 2 years, he was exposed occupationally, as a graphics worker, exclusively to two solvents containing 100% methyl ethyl ketone. The information regarding the composition of the solvents used …
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