This article requires a subscription to view the full text. If you have a subscription you may use the login form below to view the article. Access to this article can also be purchased.
Trigeminal sensory neuropathy (TSN) may be a feature of connective tissue disorders and is frequently associated with progressive systemic sclerosis or mixed connective tissue disease (MCTD). [1,2] The pathogenesis of TSN is unknown, and there is limited information on the anatomic site of the pathologic process. Lecky et al [1] proposed lesions of both the Gasserian ganglion and the peripheral portions of the trigeminal nerve. We report a patient with TSN and MCTD where neuroimaging and electrophysiological studies suggested a lesion in the cisternal part of the nerve including the Gasserian ganglion.
Case report.
A 31-year-old man was well until August 1990, when he noticed bilateral burning sensations around his mouth followed by numbness of cheeks, tongue, and oral cavity and loss of taste. Neurologic examination showed a decreased perception of pinprick, light touch, and temperature in the territory of the second and third divisions of the trigeminal nerve on both sides. Taste was impaired. Cranial motor functions and reflexes were intact. Laboratory investigation included normal sedimentation rate, blood count, electrolytes, coagulation tests, and liver and muscle enzymes. The ANA titer was 1:640 with a speckled pattern; antibodies to both extractable nuclear antigens (ENA) and ribonucleoprotein (RNP) were negative. …
AAN Members
We have changed the login procedure to improve access between AAN.com and the Neurology journals. If you are experiencing issues, please log out of AAN.com and clear history and cookies. (For instructions by browser, please click the instruction pages below). After clearing, choose preferred Journal and select login for AAN Members. You will be redirected to a login page where you can log in with your AAN ID number and password. When you are returned to the Journal, your name should appear at the top right of the page.
AAN Non-Member Subscribers
Purchase access
Letters: Rapid online correspondence
REQUIREMENTS
You must ensure that your Disclosures have been updated within the previous six months. Please go to our Submission Site to add or update your Disclosure information.
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
You May Also be Interested in
Alert Me
Recommended articles
Idiopathic trigeminal sensory neuropathy with gadolinium enhancement in the cisternal segment
Inflammatory trigeminal sensory neuropathy mimicking trigeminal neurinoma
Taste loss as an initial symptom of Guillain-Barre syndrome
Practice Parameter: The diagnostic evaluation and treatment of trigeminal neuralgia (an evidence-based review)