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2000;38(9):1207 - 15所示。
doi: 10.1016 / s0028 - 3932 (00) 00034 - 8。

非语言的语义障碍在语义痴呆

从属关系

非语言的语义障碍在语义痴呆

年代Bozeatet al。 这项研究 2000年

文摘

语义痴呆患者的临床表现是由障碍和语言理解能力差。尽管许多研究人员认为,这些病人受损的理解非语言以及语言刺激,语义恶化的证据主要来自任务,包括某种形式的语言输入或输出。很少有研究调查语义障碍完全使用非语言评估和少数例外基于结果从单例([3]:Breedin SD,萨弗兰EM, Coslett HB。逆转的具体性效应与语义痴呆病人。认知神经心理学11:617 1994;660年,[12]:格雷厄姆KS,贝克尔JT,帕特森K,霍奇斯小了字:原发性进行性失语的案子吗?:帕金,编辑器。案例研究的神经心理学记忆,东苏塞克斯:劳伦斯•Erlbaum 1997。第110 - 83页。[21]:Lambon拉尔夫,霍华德·d·檀古记失语或语义痴呆?模拟和评估贫困言语理解的进步的流利性失语。认知神经心理学,(压)。 This study employed sound recognition and semantic association tasks to investigate the nature of the verbal and non-verbal comprehension deficit in 10 patients with semantic dementia. The patients were impaired on both verbal and non-verbal conditions of the assessments, and their accuracy on these tasks was directly related to their scores on a range of other tests requiring access to semantic memory. Further analyses revealed that performance was graded by concept and sound familiarity and, in addition, identified significant item consistency across the different conditions of the tasks. These results support the notion that the patients' deficits across all modalities were due to degradation within a single, central network of conceptual knowledge. There were also reliable differences between conditions. The sound-picture matching task proved to be more sensitive to semantic impairment than the word-picture matching equivalent, and the patients performed significantly better on the picture than word version of a semantic association test. We propose that these differences arise directly from the nature of the mapping between input modality and semantic memory. Words and sounds have an arbitrary relationship with meaning while pictures benefit from a degree of systematicity with conceptual knowledge about the object.

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