TY - T1的动脉粥样硬化的作用,凝程度上,和半影卷在缺血性中风摩根富林明头痛——神经学乔-神经病学SP - 1124 LP - 1130 - 10.1212 / WNL。首页0000000000003092六世- 87 - 11盟Hendrikus j·Os AU -英奇a·穆德盟艾琳c . van der Schaaf AU - l .贾普Kappelle盟Birgitta k Velthuis盟-亚历山大Broersen盟- 1 a . Vos盟-吉塞拉·m·吉塞拉盟Wouter Schonewille AU -米歇尔·d·法拉利盟啤酒Algra AU -玛丽安嗜van Walderveen盟Marieke J.H. Wermer Y1 - 2016/09/13 UR - //www.ez-admanager.com/content/87/11/1124.abstract N2 -目的:调查大血管动脉粥样硬化的作用,血凝程度,半影体积与缺血性中风患者的头痛。首页方法:在这个横断面研究,我们进行了41 CT, CT血管造影(CTA)和CT灌注(CTP)在荷兰急性中风研究的284名参与者和莱顿中风组缺血性中风后9小时内发病。我们收集的头痛特点使用半结构化问卷前瞻性。在颅外动脉粥样硬化被评估的评估斑块和颅内血管和量化颅内颈动脉钙化。凝凝负担程度估计的分数通过CTP CTA和半影卷。我们计算风险比率(RRs)调整(aRR)使用多变量泊松回归可能的混杂因素。结果:头痛在中风在109/284(38%)的参与者。头痛患者不流行在颅外动脉粥样硬化的患者,比前循环(35% vs 48%;RR 0.72;95%可信区间(CI) 0.54 - -0.97)。颅内动脉粥样硬化的动脉也伴随着头痛,但这种关联并不显著。 Penumbra volume (aRR 1.08; 95% CI 0.63–1.85) and clot extent (aRR 1.02; 95% CI 0.86–1.20) were not related with headache.Conclusions: Headache in the early phase of ischemic stroke tends to occur less often in patients with atherosclerosis than in patients without atherosclerosis in the large cerebral arteries. This finding lends support to the hypothesis that vessel wall elasticity is a necessary contributing factor in the occurrence of headache during acute ischemic stroke.aRR=adjusted risk ratio; ASPECTS=Alberta Stroke Program Early CT Score; CBS=clot burden score; CBV=cerebral blood volume; CI=confidence interval; CTA=CT angiography; CTP=CT perfusion; DUST=Dutch Acute Stroke Study; ICA=internal carotid artery; LUMC=Leiden University Medical Center; mRS=modified Rankin Scale; MTT=mean transit time; NCCT=noncontrast CT; NIHSS=NIH Stroke Scale; RR=risk ratio; SDs=spreading depolarizations ER -