@article {MoscovichP05.015作者={马里亚纳Moscovich雷纳托穆尼奥斯和Helio Teive斑鳟属Raskin吉林刘和凯伦·麦克法兰Tetsuo Ashizawa和安德鲁·李和劳拉Silveira-Moriyama}, title ={调查嗅觉损害小脑性共济失调(P05.015)},体积={78}={1}补充数量,页面= {P05.015——P05.015} ={2012},出版商= {Wolters Kluwer健康,公司代表美国神经病学学会},文摘={摘要目的:探讨小脑性共济失调的嗅觉障碍。首页背景的主要临床表现脊髓小脑的共济失调(SCA)由于小脑的参与及其连接特性。小脑活动一直观察到在嗅觉功能成像研究,但负责此连接的解剖路径尚未阐明。先前的研究已经表明嗅觉赤字SCA2、Friedreich {\ textquoteright}共济失调和共济失调小群体的多样化的病因。设计/方法:以前翻译的16项气味鉴别试验验证Sniffin {\ textquoteright}棒(SS-16)是用来评估嗅觉36个常染色体显性共济失调(ADCA), 31个未知共济失调患者并与帕金森{\ textquoteright} 106年代疾病组(PD)患者和218名健康对照组。结果:所有392例证明SS-16共济失调的得分显著低于对照组(p \ < 0.001, 95 \ % CIβ= 0.55 - 1.90)和共济失调的显著高于PD (p \ < 0.001, 95 \ % CIβ= -4.58 - -3.00)当调整年龄(p = 0.001, 95 \ % CIβ= -0.05 - -0.01),性别(p = 0.19)和吸烟史(p = 0.41)。结论:气味识别共济失调患者减少,但不要在特发性帕金森病一样的程度,进一步的研究是必要的确认中嗅觉减退的存在纯粹的小脑性共济失调。披露:Moscovich博士没有披露。穆尼奥斯博士没有披露。Teive博士没有披露。拉斯金博士没有披露。刘博士没有披露。麦克法兰博士没有披露。 Dr. Ashizawa has nothing to disclose. Dr. Lees has received personal compensation for activities with Genus, Novartis, Teva, Meda, Boehringer Ingelheim, GlaxoSmithKline, Ipsen, Lundbeck, Allergan, Orion, BIAL, Noscira and Roche. Dr. Lees has received research support from the PSP Association and Weston Trust - The Reta Lila Howard Foundation. Dr. Silveira-Moriyama has nothing to disclose.Wednesday, April 25 2012, 14:00 pm-19:00 pm}, issn = {0028-3878}, URL = {//www.ez-admanager.com/content/78/1_Supplement/P05.015}, eprint = {//www.ez-admanager.com/content}, journal = {Neurology} }

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