PT -期刊文章盟胡里奥可•福尔兰正AU -默文Vergouwen AU -弗兰克银TI -白细胞计数作为一个标记中风的严重程度和临床结果在急性缺血性中风(P03.011) DP - 2012年4月24日TA -神经病学PG - P03.011 P03.011 VI - 78 IP - 1补充4099 - //www.ez-admanager.com/content/78/1_Supplement/P03.011.short 4100 首页- //www.ez-admanager.com/content/78/1_Supplement/P03.011.full所以Neurology2012 4月24日;78 AB -目的:我们假设更高程度的白细胞增多是一个糟糕的标志在急性缺血性中风临床结果和预后。据说背景的炎症反应程度与急性缺血性中风的严重程度有关。设计/方法:回顾性病例系列包括数据从3级注册加拿大中风网络的连续的缺血性中风患者承认一个安大略省中风研究中心和一个中心在新斯科舍。我们包括所有连续与缺血性中风患者入院7月/ 2003 / 2008年3月。患者最终诊断non-stroke,蛛网膜下腔出血,或颅内出血,患者使用糖皮质激素,癌症患者,患者使用一个anti-convulsivant药物之前承认,病人使用抗生素在入学之前,患者肾透析,肝硬化患者,怀孕的患者被排除在外。Results: Higher white blood cell count (WBC) is significantly associated with greater degree of impairment (p<0.0001), greater degree of disability (p=0.0005), higher risk of a Total Anterior Circulation Stroke (p<0.0001) and higher 30-day mortality (p<0.0001) after adjustment for major potential confounders. The Kaplan-Meier curves indicate that abnormal WBC is associated with higher mortality after acute ischemic stroke (p=0.001). However, there was no significant association between WBC and length of stay in the acute stroke care center (p=0.9877).Conclusions: The results of our study indicate that a higher WBC on the initial admission an acute ischemic stroke is associated with poorer prognosis with respect to the degree of impairment and disability, risk of further ischemic stroke and 30-day mortality. Given the large sample size of this prospectively collected database, those results were properly adjusted for several major potential confounders. Of note, the length of stay in the acute stroke care center was not adversely affected by WBC on admission.Supported by: Funded by scholarships and fellowships from University of Toronto.Disclosure: Dr. Furlan has nothing to disclose. Dr. Vergouwen has nothing to disclose. Dr. Silver has nothing to disclose.Tuesday, April 24 2012, 14:00 pm-18:30 pm