首页TY - JOUR T1 - Examining Predictors of the Physical and Mental Components of Quality of Life in the TOP MS Study (P07.103) JF - Neurology JO - Neurology SP - P07.103 LP - P07.103 VL - 78 IS - 1 Supplement AU - Merrikay Oleen-Burkey AU - Howard Zwibel AU - Patricia Coyle AU - Douglas Denney Y1 - 2012/04/26 UR - //www.ez-admanager.com/content/78/1_Supplement/P07.103.abstract N2 - Objective: To assess the most effective predictors of the Physical Component Score (PCS) and Mental Component Score (MCS) of the SF-12 used to assess quality of life in the Treatment Optimization in MS (TOP MS) Study.Background Several MS patient characteristics may be associated with the PCS and MCS including patient age, disability status and levels of fatigue, perceived cognitive deficits and depression.Design/Methods: Potential participants for the TOP MS study were identified at specialty pharmacies with medication therapy management programs.签名知情同意表交回药店学习注册生成登录指令24个月基数和定时间隔时,注册参赛者收到提醒回复调查,包括SF-12健康调查、自报EDSS系统、Fatigue重度标度自报响应直接输入研究数据库多回归分析用于识别PCS和MCS.Results预测器:对预测PCS高度有效的病人特征数组包括病人年龄、自报EDSS和FSS评分、PDQ和PHQPCS唯一预测器是自报EDSS评分(p <.0001)和FSS评分(p <.0001)独立预测器同数组预测器预测监控监效果也很高(调整R2=467,p <.001)。MCS独有预测器自报EDSSsssssssssssssssmOleen-Burkey因与Teva神经科学有关的活动而获得个人补偿博士Oleen-Burkey持有Pfizer公司和TevaNeuroscience股票和/或股票选择权博士Oleen-Burkey接受Teva神经科学研究支持博士兹维贝尔因Serono公司和TevaNeuroscience公司的活动得到了个人补偿博士兹维贝尔接受Teva神经科学研究支持博士Coyle因Acorda解析公司、Avanir药厂、Bayer药厂公司、BiogenIdec公司、Genzyme公司、Novartis公司、Questcor公司、Roche诊断公司、Sanofi-Aventis药厂和TevaNeurosci博士Coyle以编辑身份为NEURA获得个人补偿博士Coyle从Serono公司、Novartis公司和Sanofi-Aventis药厂公司获得研究支持博士登尼因与TevaNeuroscience Inc.咨询师Drenney从Serono Inc.Thursday,2012年4月26日14:00下午18:30ER-